Content: Stress gastroduodenal ulcer may develop under the great impact of increased adrenocorticotropic hormone production followed by increased corticosteroid release. These hormones reduce gastric mucin production and change its qualitative composition, affects damaged cells regeneration and reduces gastric blood flow. In other words, natural barrier becomes weakened whereas aggression factor intensifies which leads to stomach ulcer.

Such ulcer is also called symptomatic ulcer due to the fact that it is not typically accompanied by pain and dyspeptic syndrome.

Conclusion: Stress ulcer is treated with PPI (proton pump inhibitor) (Rabeprazole, Esomeprazole, Omeprazole, etc.), medication that stimulates mucin and has enveloping effect (Rebamipide, De-Nol, etc.). It is also possible to use adsorbents (Smecta, Enterosgel, Phosphalugel, etc.).

Reference: F. Komarov, M. Osadchuk, A. Osadchuk (2010). "Practical gastroenterology. Part II. Stomach diseases". 119.